1. Pharmaceuticals and Drug Development

Access Denied

Written by Posted on Less than 0 min read


Access Denied

You don’t have permission to access ” on this server.

Reference #18.6c6cd317.1754300369.4e0a6554

Member since

More from Admin

Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Blood test eases diagnosis of invasive mold disease

For people with weakened immune systems, common molds lurking in the environment — in the soil, along damp walls or on a forgotten apple — can cause dangerous infections deep inside the body. These invasive mold infections can quickly become fatal without treatment, yet they are difficult to diagnose without invasive procedures such as a […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Nature’s viny vampire: Discovering what drives parasitic Cuscuta campestris

The parasitic vine Cuscuta campestris grows by latching onto the stems and leaves of plants and inserting organs called haustorium into the host plant tissues to draw nutrients. The haustorium is formed when ion channels in the cell membrane are stimulated during coiling and induce a reaction within the cell. Further, Cuscuta campestris has many […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Low stream diatom biodiversity potentially decreasing stream oxygen production in remote islands

Benthic diatoms are the most important and biodiverse primary producers in streams and comprise the basis for the food webs, fueling animals such as insects and stream fishes including trout. “It is known that highly biodiverse diatom communities are very efficient in producing oxygen” says Professor Janne Soininen from University of Helsinki. “Islands have long […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Researchers discover gene variants that determine speed of graying in horses

Scientists from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) and Uppsala University in Sweden now understand why some gray horses turn completely white as they age, while others remain an eye-catching “dappled” gray color. As published in the journal Nature Communications, the deciding factor is the number of copies of a […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

World’s largest bat organoid platform paves the way for pandemic preparedness

Did you know that more than 75% of new infectious diseases affecting humans originally come from animals? Bats, in particular, are natural hosts to some of the world’s most dangerous viruses, including those responsible for COVID-19 (SARS-CoV-2), MERS-CoV, influenza A, and hantavirus outbreaks. Yet, despite their importance, scientists have long struggled to study how these […]
Written by
Frozen in time: Transparent worms keep genes in sync for 20 million years
  1. Life Sciences

Frozen in time: Transparent worms keep genes in sync for 20 million years

Two species of worms have retained remarkably similar patterns in the way they switch their genes on and off despite having split from a common ancestor 20 million years ago, a new study finds. The findings appear in the June 19 issue of the journal Science. “It was just remarkable, with this evolutionary distance, that […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Found at last: Bizarre, egg-laying mammal finally rediscovered after 60 years

More than sixty years after it was last recorded, an expedition team has rediscovered an iconic, egg-laying mammal in one of the most unexplored regions of the world. Attenborough’s long-beaked echidna, named after famed broadcaster Sir David Attenborough, was captured for the first time in photos and video footage using remote trail cameras set up […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

New Zealand’s flightless birds are retreating to moa refuges

Researchers have found New Zealand’s endangered flightless birds are seeking refuge in the locations where six species of moa last lived before going extinct. An international team of researchers, led by scientists from the University of Adelaide, used fossils and computer modelling to make the discovery, shedding light on a mystery with important conservation benefits. […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

System to auto-detect new variants will inform better response to future infectious disease outbreaks

Researchers have come up with a new way to identify more infectious variants of viruses or bacteria that start spreading in humans — including those causing flu, COVID, whooping cough and tuberculosis. The new approach uses samples from infected humans to allow real-time monitoring of pathogens circulating in human populations, and enable vaccine-evading bugs to […]
Written by
Scientists uncover new way viruses fight back against bacteria
  1. Life Sciences

Key role of plant-bacteria communication for the assembly of a healthy plant microbiome supporting sustainable plant nutrition

In an interdisciplinary study, researchers discovered that symbiotic bacteria communicate with legume plants through specific molecules and that this communication influences which bacteria grow near the plant roots. The findings provide insights into how plants and soil bacteria form beneficial partnerships for nutrient uptake and resilience. These results are a step towards understanding how communication […]
Written by
  1. Biology

Intersection of GPCR trafficking and cAMP signaling at endomembranes

GPCRs comprise the largest family of signaling receptors and control essentially every physiological process. Many biochemical reactions underlying GPCR signaling are now elucidated to atomic resolution in cell-free preparations, but how elemental signaling reactions are organized in intact cells remains less clear. Significant progress has been made toward bridging this knowledge gap by leveraging new […]
Written by
  1. Biology

The underrated impact of humidity

Governments, medical institutions and other bodies require accurate models on health-related matters in order to better organize their activities. Climate change has measurable impacts on society, including on human mortality. However, current models to assess the health impacts of climate change do not account for every environmental parameter, especially humidity, which could influence heat stress […]
Written by
  1. Biology

Directed stochasticity: Building biomolecular condensates in the right place

Controlling biomolecular condensate formation within the nucleus is critical for genome function. In this issue, Xu et al. (https://doi.org/10.1083/jcb.202401036) report that KPNA3 promotes histone locus body formation and expression of replication-dependent histone genes by both importing NPAT into the nucleus and preventing NPAT condensation from improperly occurring in the cytoplasm. Admin Member since October 11, […]
Written by
  1. Biology

The unexpected structure and dynamics of vimentin networks

Bhattacharyya and Klumpp discuss exciting new observations of the native intermediate filament network in cells shown in Renganathan et al. (https://doi.org/10.1083/jcb.202406054) in this issue. Combining two powerful imaging techniques, Renganathan et al. examine the organization and dynamics of vimentin filaments in unprecedented detail. Admin Member since October 11, 2023 Loading + Follow Following
Written by
  1. Biology

Pex30-dependent membrane contact sites maintain ER lipid homeostasis

In eukaryotic cells, communication between organelles and the coordination of their activities depend on membrane contact sites (MCS). How MCS are regulated under the dynamic cellular environment remains poorly understood. Here, we investigate how Pex30, a membrane protein localized to the endoplasmic reticulum (ER), regulates multiple MCS in budding yeast. We show that Pex30 is […]
Written by
  1. Biology

Distinct roles of two homologous kinesins in mammalian motile cilia

How do the two kinesin-9 members Kif6 and Kif9 function in mammalian cilia? Ou and colleagues discuss new work from Fang et al. (https://doi.org/10.1083/jcb.202312060) showing that Kif6 is an active motor while Kif9 serves as a stationary regulator, both of which are essential for cilia motility. Admin Member since October 11, 2023 Loading + Follow […]
Written by
Takeda Announces Topline Results of Phase 3 ADMIRE-CD II Trial of Alofisel® (darvadstrocel) in Complex Crohn’s Perianal Fistulas
  1. Clinical

Zibotentan/Dapagliflozin Combination Demonstrated Significant Albuminuria Reduction in Patients with Chronic Kidney Disease and Proteinuria in ZENITH-CKD Phase IIb Trial

November 3, 2023 — Combination of zibotentan with dapagliflozin showed statistically significant and clinically meaningful reductions in urinary albumin-to-creatinine ratio (UACR), used to assess albuminuria, at 12 weeks compared with dapagliflozin alone. After 12 weeks of treatment, the Phase IIb ZENITH-CKD trial showed that the UACR difference of zibotentan/dapagliflozin versus dapagliflozin alone (n=177) was –33.7% […]
Written by
  1. Clinical

Unlocking the Benefits: Understanding Clinical Studies That Pay

Clinical studies that pay are research studies conducted by pharmaceutical companies or other organizations to evaluate the safety and effectiveness of new drugs, treatments, or medical devices. These studies recruit volunteers who are willing to participate in the research and compensate them financially for their time and participation. While some people may have reservations about […]
Written by
  1. Nonclinical

From the clinic to the boardroom: Thriving in nonclinical career options for physicians

Title: From the Clinic to the Boardroom: Thriving in Nonclinical Career Options for Physicians Introduction: For many physicians, the path from medical school to clinical practice has been the traditional route. However, with the evolving healthcare landscape and the growing demand for healthcare leaders in nontraditional settings, an increasing number of doctors are embracing nonclinical […]
Written by
Next
No Comments
Leave a comment Cancel
Comments to: Access Denied

Login

Welcome to Life Science News!
"Explore the Latest Discoveries and Breakthroughs in Life Science with Life Science News!"
Read Smart, Save Time
Pick all the topics you are interested in to fill your homepage with stories you'll love.
Join our community
Registration is closed.