1. Biology

Arc spreads Crumbs: Spatial restriction of tissue invagination to form a thin epithelial tube

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In this issue, Kim et al. (https://doi.org/10.1083/jcb.202409078) report that the scaffold protein Arc acts through Crumbs to spatially restrict where actomyosin-based apical constriction occurs across the invaginating Drosophila salivary gland. This restriction is needed for a long, thin tube to form.

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